University of Houston · Biomedical Engineering
Mohan Lab
Translational biomedical research in autoimmunity, cancer, and chronic disease. We combine immunology, high-plex omics, data science, and bioengineering to study disease mechanisms and improve diagnosis.
Research participation
Digital phenotyping study
Female UH students aged 18+: help researchers study stress, cognition, and digital health over three months. A Fitbit is provided.
Research overview
Connecting disease biology with measurement.
The lab studies molecular mechanisms of disease and develops biomarkers, assays, and computational methods for diagnosis and monitoring.
Research areas
Current areas of investigation
Projects span autoimmune disease, cancer, chronic illness, diagnostics, and biomedical engineering.
01
Disease mechanisms
Spatial and high-plex omics reveal the molecular systems driving lupus, kidney injury, cancer, and inflammatory disease.
02
Biomarkers and diagnostics
Liquid biopsy and biomarker programs seek precise, less invasive ways to diagnose disease and monitor activity.
03
Translational bioengineering
AI, microfluidics, 3D models, and rapid tests turn biological findings into tools for research and clinical care.
Research
Selected projects
OmicsSpatial Proteomic, Transcriptomic, and Metabolomic Investigations of Lupus Nephritis
Lupus nephritis (LN) is a renal manifestation of Systemic Lupus Erythematosus, an autoimmune kidney disease in which molecular changes within glomeruli and tubulointerstitial compartments drive disease…Explore project
AI & DigitalDeciphering the Molecular Basis of Blood-Brain Barrier Disruption and Cognitive Decline in NPSLE
Neuropsychiatric systemic lupus erythematosus (NPSLE) represents a severe complication of systemic lupus erythematosus (SLE), impacting both the central and peripheral nervous systems.Explore project
AI & DigitalDigital phenotyping as a surrogate for Patient-Reported Outcomes (PROs) in Rheumatic Disease Management (pilot study will be conducted in healthy recruits)
Lupus nephritis (LN) and other rheumatic diseases are characterized by fluctuating disease activity, requiring prompt changes in therapy.Explore project
AI & DigitalAI-Aided Assessment of Renal Pathology in Lupus Nephritis
Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus and remains a major cause of chronic kidney disease and kidney failure.Explore project
People
Faculty, staff, and trainees
Engineers, data scientists, physicians, and molecular researchers work together across projects, methods, and stages of training.
News
Recent lab activity
June 2026Global collaboration in Sri Lanka
Dr. Mohan met with collaborator Prof. Ranil de Silva in June 2026.
June 2026Scientific exchange at A*STAR Singapore
A June 2026 visit with Prof. KP Lam and Dr. Frank Tay.
2026Celebrating the people behind the science
The lab gathered to wish Dr. Diptish well as he left for residency.
Opportunities
Research training at Mohan Lab
Information for high school interns, undergraduates, graduate students, and visiting scholars.